Publications

2019

  • Minimizing taxonomic and natural product redundancy in microbial libraries using MALDI-TOF MS and the bioinformatics pipeline IDBac. Costa, M. S.*; Clark, C. M.*; Omarsdottir, S.; Sanchez, L. M.; Murphy, B. T.  J. Nat Prod. 2019, 82, 2167-2173.

  • Using the open-Source MALDI TOF-MS IDBac pipeline for analysis of microbial protein and specialized metabolite data. Clark, C. M.*; Costa, M. S.*; Conley, E.*; Li, E.; Sanchez, L. M.; Murphy, B. T. J. Vis. Exp. 2019, 147, e59219. 

  • Genome sequence of marine-derived Streptomyces sp. strain F001, a producer of akashin A and diazaquinomycins. Braesel, J.; Clark, C. M.; Kunstman, K. J.; Green, S. J.; Maienschein-Cline, M.; Murphy, B. T.; Eustaquio, A. S.  Microbiol. Resour. Announc. 2019, 8, e00165-19.

  • Diazaquinomycin biosynthetic gene clusters from marine and freshwater actinomycetes.​ Braesel, J.; Lee, J-H.; Arnould, B.; Murphy, B. T.; Eustaquio, A. S. J. Nat. Prod. 2019, 82, 937-946.

  • Antimicrobial Lavandulylated Flavonoids from a Sponge-Derived Streptomyces sp. G248 in East Vietnam Sea. Cao, D. D.; Trinh, T. T.; Mai, H. D.; Vu, V. N.; Minh, H. L.; Thi, Q. V.; Nguyen, M. A.; Duong, T. T.; Tran, D. T.; Chau, V. M.; Ma, R.; Shetye, G.; Cho, S.; Murphy, B. T.; Pham, V. C.  Mar. Drugs. 2019, 17, 529.

  • Antimicrobial Lavandulylated Flavonoids from a Sponge-Derived Streptomyces sp. G248 in East Vietnam Sea. Cao, D. D.; Trinh, T. T.; Mai, H. D.; Vu, V. N.; Minh, H. L.; Thi, Q. V.; Nguyen, M. A.; Duong, T. T.; Tran, D. T.; Chau, V. M.; Ma, R.; Shetye, G.; Cho, S.; Murphy, B. T.; Pham, V. C.  Mar. Drugs. 2019, 17, 529.

  • Viral composition and context in metagenomes from biofilm and suspended growth municipal wastewater treatment plants. Petrovich, M. L.; Maamar, S. B.; Hartmann, E. M.; Murphy, B. T.; Poretsky, R. S.; Wells, G. F.  Microb. Biotechnol. 2019, 1-13.

2018

  • Deconvolution of E/Z tetrahydroisoquinoline amide rotamers and conformers from a marine-derived Streptomyces strain.​ Nepomucenu, V. M.; Kim, H.; Ding,Y.; Liu, H.; Sadek, M.; Ferreira, D.; Omarsdottir, S.; Murphy, B. T. Tetrahedron. 2018, 74, 7421-7425.

  • Assessing the efficiency of cultivation techniques to recover natural product biosynthetic gene populations from sediment.  Elfeki, M.; Alanjary, M.; Green, S.; Ziemert, N.; Murphy, B. T. ACS Chem. Biol. 2018, 13, 2074-2081.

  • Coupling MALDI-TOF mass spectrometry protein and specialized metabolite analyses to rapidly discriminate bacterial function. Clark, C. M.; Costa, M. S.; Sanchez, L. M.; Murphy, B. T. Proc. Natl. Acad. Sci. 2018, 115, 4981-4986. 

  • Irilone from Red Clover (Trifolium pratense) potentiates progesterone signaling.  Lee, J.-H.; Dean, M.; Burdette, J. E.; Murphy, B. T. J. Nat Prod. 2018, 81, 1962-1967.

  • Braesel, J.; Crnkovic, C. M.; Kunstman, K. J.; Green, S. J.; Maienschein-Cline, M.; Orjala, J.; Murphy, B. T.; Eustaquio, A. S. Complete genome of Micromonospora sp. Strain B006 reveals biosynthetic potential of a Lake Michigan Actinomycete. J. Nat. Prod. 2018, 81, 2057-2068.

  • Antibiotic resistance genes show enhanced mobilization through suspended growth and biofilm-based wastewater treatment processes. Petrovich, M.; Chu, B.; Wright, D.; Griffin, J.; Elfeki, M.; Murphy, B. T.; Poretsky, R.; Wells, G. FEMS Microbiol. Ecol. 2018, 94, fiy041. 

  • Canvass: a crowd-sourced, natural product screening library for exploring biological space. 2018, ACS Central Sci. 2018, 4, 1727-1741.  Kearney, S. ; Zahoránszky-Kőhalmi, G. ; Brimacombe, K.; Henderson, M.; Lynch, C.;  Zhao, T.; Wan, K.; Itkin, Z.; Dillon, C.; Shen, M.; Cheff, D.; Lee, T.; Bougie, D.; Cheng, K.; Coussens, N.; Dorjsuren, D.; Eastman, R.; Huang, R.; Iannotti, M.; Karavadhi, S.; Klumpp-Thomas, C.; Roth, J.; Sakamuru, S.; Sun, W.; Titus, S.; Yasgar, A.; Zhang, Y.-Q.; Zhao, J.; Andrade, R.; Brown, M.; Burns, N.; Cha, J.; Mevers, E.; Clardy, J.; Clement, J.; Crooks, P.; Cuny, G.; Ganor, J.; Moreno, J.; Morrill, L.; Picazo, E.; Susick, R.; Garg, N.; Goess, B.; Grossman, R.; Hughes, C.; Johnston, J.; Joullié, M.; Kinghorn, D.; Kingston, D.; Krische, M.; Kwon, O.; Maimone, T.; Majumdar, S.; Maloney, K.; Mohamed, E.; Murphy, B. T.; Nagorny, P.; Olson, D.; Overman, L.; Brown, L.; Snyder, J.; Porco, J.; Rivas, F.; Ross, S.; Sarpong, R.; Sharma, I.; Shaw, J.; Xu, Z.; Shen, B.; Shi, W.; Stephenson, C.; Verano, A.; Tan, D.; Tang, Y.; Taylor, R.; Thomson, R.; Vosburg, D.; Wu, J.; Wuest, W.; Zakarian, A.; Zhang, Y.; Ren, T.; Zuo, Z.; Inglese, J.; Michael, S.; Simeonov, A.; Zheng, W.; Shinn, P.; Jadhav, A.; Boxer, M.; Hall, M.; Xia, M.; Guha, R.; Rohde, J.

2017

  • Metagenomic analysis reveals the impact of wastewater treatment plants on the dispersal of microorganisms and genes in aquatic sediments. Chu, B; Petrovich, M.; Chaudhary, A; Wright, D.; Murphy, B. T.; Wells, G.; Poretsky, R.  Appl. Environ. Microbiol. 2017, 84, e02168-17.

2016

  • Phytosteroids beyond estrogens: Regulators of reproductive and endocrine function in natural products. Dean, M. Murphy, B. T., Burdette, J. E.  Mol Cell Endocrinol. 2016, 442, 98.

  • Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

    • Wang, M.; Carver, J.; Phelan, V. V.; Sanchez, L. M.; Garg, N.; Peng, Y.; Watrous, J.; Nguyen, D. D.; Kapono, C. A.; Luzzatto-Knaan, T.; Porto, C; Bouslimani, A.; Melnik, A. V.; Meehan, M. J.; Liu, W-T.; Crüsemann, M.; Boudreau, P. D.;’  Esquenazi, E.; Sandoval-Calderón, M.; Kersten, R. D.; Pace, L. A.; Quinn, R. A.; Duncan, K. R.; Hsu, C-C.; Floros, D. J.; Gavilan, R. G.; Kleigrewe, K.; Northen, T.; Dutton, R. J.; Parrot, D.; Carlson, E. E.; Aigle, B.; Michelsen, C. F.; Jelsbak, L.;  Sohlenkamp, C.; Pevzner, P.; Edlund, A.; McLean, J.; Piel, J.;   Murphy, B. T.; Gerwick, L.; Liaw, C-C.; Yang, Y-L.; Humpf, H-U.; Maansson, M.; Keyzers, R. A.; Sims, A. C.; Johnson, A. R.; Sidebottom, A. M.; Sedio, B. E.; Klitgaard, A.; Larson, C. B.; Boya, C. A.; Torres-Mendoza, D.; Gonzalez, D. J.; Silva, D. B.; Marques, L. M. M.; Demarque, D. P.; Pociute, E.; O’Neill, E. C.; Briand, E.; Helfrich, E. J. N.; Granatosky, E. A.; Glukhov, E.; Ryffel, F.; Houson, H.; Mohimani, H.; Kharbush, J. J.; Zeng, Y.; Vorholt, J. A.; Kurita, K. L.; Charusanti, P.; McPhail, K. L.; Nielsen, K. F.; Vuong, L.; Elfeki, M.; Traxler, M. F.; Engene, N.; Koyama, N.; Vining, O. B.; Baric, R.; Silva, R. R.; Mascuch, S. J.; Tomasi, S.; Jenkins, S.; Macherla, V.; Hoffmann, T.; Agarwal, V.; Williams, P. G.; Dai, J.; Neupane, R.; Gurr, J.; Rodríguez, A. M. C.; Lamsa, A.; Zhang, C.; Dorrestein, K.; Duggan, B. M.; Almaliti, J.; Allard, P-M.; Wolfender, J-L.; Peryea, T.; Nguyen, D-T.; VanLeer, D.; Shinn, P.; Jadhav, A.; Müller, R.; Waters, K. M.; Shi, W.; Liu, X.; Zhang, L.; Knight, R.; Jensen, P. R.; Palsson, B. O.; Pogliano, K.; Linington, R. G.; Gutiérrez, M.; Lopes, N. P.; Gerwick, W. H.; Moore5, B. S.; Dorrestein, P. C.; Bandeira, N.  Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.  Nature Biotechnology, 2016 35, 828.

  • Antimicrobial metabolites from a marine-derived actinomycete in Vietnam’s East Sea. Thi, Q. V., Maia, H. D., Le, C. V., Hong, M. le T., Murphy, B. T., Chau, V. M., Pham, V. C.  Nat. Prod. Commun. 2016, 1, 49.

2015

  • Deuteromethylactin B from a freshwater-derived Streptomyces sp. Shaikh, A., Elfeki, M., Landolpha, S., Tanouye, U., Green, S. J., Murphy, B. T.  Nat. Prod. Sci. 2015, 21, 1.

  • A pimarane diterpene and cytotoxic angucyclines from a marine-derived Micromonospora sp. in Vietnam’s East Sea. Mullowney, M. W., Ó hAinmhire, E., Tanouye, U., Burdette, J. E., Pham, V. C., Murphy, B. T. Marine Drugs, 2015, 13, 5815.

  • Diaza-anthracene antibiotics from a freshwater-derived actinomycete with selective antibacterial activity toward M. tuberculosis. Mullowney, M.; Hwang, C.; Newsome, A.; Wei, X.; Tanouye, U.; Wan, B.; Carlson, S.; Barranis, N.; Ó hAinmhire, E.; Chen, W.-L.; Krishnamoorthy, K.; White, J.; Blair, R.; Lee, H.; Burdette, J.; Rathod, P.; Parish, T.; Cho, S.; Franzblau, S.; Murphy, B. T.  ACS Inf. Dis. 2015, 1, 168. *Article featured on cover April 2015 issue. 

 

  • Phylum-specific regulation of resistomycin production in a Streptomyces sp. via microbial co-culture. Carlson, S. K.; Tanouye, U., Omarsdottir, S., and Murphy, B.T.  J. Nat. Prod. 2015, 78, 381.

 

2014

  • Diazaquinomycins E-G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp. Mullowney, M. W.; O’hAinmhire, E. O.; Shaikh, A.; Wei, X.; Tanouye, U.; Santarsiero, B. D.; Burdette, J. E., and Murphy, B.T.  Mar. Drugs. 2014, 12, 3574.

 

 

2013

  • Tools for characterizing bacterial protein synthesis inhibitors. Orelle, C.; Carlson, S. K.; Kaushai, B.; Almutairi, M. M.; Liu, H.; Ochabowicz, A.; Quan, S.; Cuong, V. C.; Murphy, B. T.; Mankin, A. S.  Antimicrob Ag. Chemother. 2013, 57, 5994.

  • Potential chemopreventive activity of a new macrolide antibiotic from a marine-derived Micromonospora sp. Carlson, S. K.; Marler, L.; Nam, S-J.; Santarsiero, B.; Pezzuto, J.M., and Murphy, B.T. Mar. Drugs. 2013, 11, 1152.

  • Isolation and Characterization of Natural Blue Pigments from Underexplored Sources. Newsome, A.; Murphy, B. T.; van Breemen, R., from Physical Methods in Food Analysis, ACS Books, March 2013.

 

Pre-2013

Kondratyuk, T., Park, E.J., Yu, R., van Breemen, R., Asolkar, R.N., Murphy, B.T., Fenical, W., and Pezzuto, J.M. Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents. Mar. Drugs. 10: 451-464, 2012.

 

Murphy, B. T.; Jensen, P.; Fenical, W.  “Marine Bacteria.” Invited chapter (1.3) from “Handbook of Marine Natural Products.” 2011, Springer, New York, NY. 

 

Murphy, B. T.; Maloney, K.; Fenical, W.  “Marine Microorganisms.” Invited chapter from “Phytochemistry and Pharmacognosy” submitted as part of the United Nations Educational, Scientific and Cultural Organization’s Encyclopedia of Life Support Systems (UNESCO-EOLSS). 2011, Oxford, UK. [email btmurphy@uic.edu for a Pdf copy]

 

Murphy, B. T.; Narender, T.; Kauffman, C.; Jenson, P.; Fenical, W.  Saliniquinones A-F, cytotoxic anthraquinone-g-pyrones from Salinispora arenicola. Aus. J. Chem. 2010, 63, 929-934. [Invited submission for special issue on marine natural products]

 

Oh, H.; Jensen, P.; Murphy, B. T.; Fiorilla, C.; Sullivan, J. F.; Ramsey, T.; Fenical, W.  Cryptosphaerolide, a cytotoxic Mcl-1 inhibitor from a marine-derived ascomycete related to the genus Cryptosphaeria.  J. Nat. Prod. 2010, 73, 998-1001.

 

Murphy, B. T.*; Cao, S.*; Brodie, P.; Maharavo, J.; Kingston, D. G. I.  Antiproliferative bistramides from Trididemnum cyclops from Madagascar.  J. Nat. Prod. 2009, 72, 1338-1340.  *Authors shared equal contribution.

 

Cao, S.*; Murphy, B. T.*; Foster, C.; Lazo, J. S.; Kingston, D. G. I.  Synthesis and activity of simplified adociaquinone B and napthoquinone derivatives against Cdc25B phosphatase.  Bioorg. Med. Chem. 2009, 17, 2276-2281.  *Authors shared equal contribution.

 

Murphy, B. T.; Slebodnick, C.; Brodie, P.; Miller, J. S.; Rasamison, V. E.; TenDyke, K.; Suh, E. M.; Kingston, D. G. I.  Antiproliferative limonoids of Malleastrum sp. from the Madagascar rainforest. J. Nat. Prod. 2008, 71, 325-329.

 

Murphy, B. T.; Cao, S.; Brodie, P.; Miller, J. S.; Ratovoson, F.; Birkinshaw, C.; Rakotobe, E.; Rasamison, V. E.; TenDyke, K.; Suh, E. M.; Kingston, D. G. I.  Antiproliferative compounds of Artabotrys madagascariensis from the Madagascar rainforest.  Nat. Prod. Res. 2008, 22, 1169-1175.

 

El-Youssef, H. M.; Murphy, B. T.; Amer, M. E.; Al-Rehaily, A. J.; Abdel-Kader, M. S.; Kingston, D. G. I.  Two new flavonol glycosides from the aerial parts of Lotus lalambensis growing in Saudi Arabia.  Nat. Prod. Sci., 2008, 14, 86-89.

 

Murphy, B. T.; Cao, S.; Norris, A.; Miller, J. S.; Ratovoson, F.; Andriantsiferana, R.; Rasamison, V. E.; Kingston, D. G. I.  Cytotoxic compounds of Schizolaena hystrix from the Madagascar rainforest. Planta Med.  2006, 72, 1235-1238.

 

Murphy, B. T.; Cao, S.; Norris, A.; Miller, J. S.; Ratovoson, F.; Andriantsiferana, R.; Rasamison, V. E.; Kingston, D. G. I. Cytotoxic flavanones of Schizolaena hystrix of the Madagascar rainforest.  J. Nat. Prod. 2005, 68, 417-419.

 

Murphy, B. T.; MacKinnon, S.; Yan, X.; Hammond, G. B.; Vaisberg, A. J.; Neto, C. C. Identification of triterpene hydroxycinnamates with in vitro antitumor activity from whole cranberry fruit (Vaccinium macrocarpon),  J. Agric. Food Chem. 2003, 51, 3541-3545.

 

Neto, C. C.; Yan, X.; Murphy, B. T.; Azogu, K.; Hammond, G. B.  Chapter 27: Fractionation, antioxidant activity and cytotoxicity of cranberry fruit extracts, Symposium Series No. 851 Food Factors in Health Promotion and Disease Prevention, ACS Books, Shahidi, F.; Ho, C.-T.; Watanabe, S.; Osawa, T.; Eds. 2003, p. 312-321.

 

Yan, X.; Murphy, B. T.; Hammond, G. B.; Vinson, J. A.; Neto, C. C. Antioxidant activities and antitumor screening of extracts from cranberry fruit (Vaccinium Macrocarpon).  J. Agric. Food Chem. 2002, 50, 5844-5849.